FREQ Antibody

• Background:

  FREQ is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. This protein is thought to be associated with secretory granules and may be involved in the regulation of neurosecretion.

• NCBI Gene ID:

  23413

• Swiss Prot:

  P62166

• Accession Number:

  NP_055101

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Zebrafish

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FREQ.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store FREQ antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  22 kDa

• Applications Notes:

  FREQ antibody can be used for detection of FREQ by ELISA at 1:312500. FREQ antibody can be used for detection of FREQ by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  NCS1

• NCBI Official Name:

  Neuronal calcium sensor 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Telford, E.A., et al., (2004) J. Biol. Chem. 279 (14), 14347-14354.

• Other Product Names:

  FREQ, FLUP, FREQ

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  17738308

• Physical Properties:

  Liquid