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CBFA2T3 Antibody

CAT: 0223-27-985Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-985Size:100 µL
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Background
The t (16;21) (q24; q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.
NCBI Gene ID
863
Swiss Prot
O75082
Accession Number
NP_787127
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CBFA2T3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CBFA2T3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
62 kDa, 71 kDa
Applications Notes
CBFA2T3 antibody can be used for detection of CBFA2T3 by ELISA at 1:312500. CBFA2T3 antibody can be used for detection of CBFA2T3 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CBFA2T3
NCBI Official Name
Core-binding factor, runt domain, alpha subunit 2; translocated to, 3
NCBI Organism
Homo sapiens
Background Reference 01
Powell, J.A., et al., (2002) Genomics 80 (3), 303-310.
Other Product Names
CBFA2T3, ETO2, MTG16, MTGR2, ZMYND4
Tested Applications
ELISA, WB
Protein ID
28872805
Physical Properties
Liquid

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