C4BPB Antibody

• Background :

  C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C.

• NCBI Gene ID :

  725

• Swiss Prot :

  P20851

• Accession Number :

  NP_000707

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human C4BPB.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction, Immunology

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Cat. No. XBL-10409 - Fetal Liver Tissue Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store C4BPB antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  28 kDa

• Applications Notes :

  C4BPB antibody can be used for detection of C4BPB by ELISA at 1:12500. C4BPB antibody can be used for detection of C4BPB by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  C4BPB

• NCBI Official Name :

  Complement component 4 binding protein, beta

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Anderson, N.L., et al., (2004) Mol. Cell Proteomics 3 (4), 311-326.

• Other Product Names :

  C4BPB, C4BP

• Tested Applications :

  ELISA, WB, IHC

• Protein ID :

  4502505

• Physical Properties :

  Liquid