RBAK Antibody

• Background :

  RBAK is a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif.

• NCBI Gene ID :

  57786

• Swiss Prot :

  Q9NYW8

• Accession Number :

  NP_066986

• Host :

  Rabbit

• Reactivity :

  Human, Dog

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RBAK.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Transcription, Cancer

• Purification :

  Antibody is purified by protein A chromatography method.

• Positive Control :

  NTERA2 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RBAK antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  83 kDa

• Applications Notes :

  RBAK antibody can be used for detection of RBAK by ELISA at 1:1562500. RBAK antibody can be used for detection of RBAK by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  RBAK

• NCBI Official Name :

  RB-associated KRAB zinc finger

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Hofman, K., et al., (2003) J. Mol. Endocrinol. 31 (3), 583-596.

• Other Product Names :

  RBAK, ZNF769

• Tested Applications :

  ELISA, WB

• Protein ID :

  13430850

• Physical Properties :

  Liquid