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NFKB2 Antibody

CAT: 0223-27-680Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-680Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
NCBI Gene ID
4791
Swiss Prot
Q00653
Accession Number
NP_002493
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFKB2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1207 - Raji Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NFKB2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
101 kDa
Applications Notes
NFKB2 antibody can be used for detection of NFKB2 by ELISA at 1:1562500. NFKB2 antibody can be used for detection of NFKB2 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
NFKB2
NCBI Official Name
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NCBI Organism
Homo sapiens
Background Reference 01
Xiao, G., et al., (2004) J. Biol. Chem. 279 (29), 30099-30105.
Other Product Names
NFKB2, p52, p105, H2TF1, LYT10, CVID10, LYT-10, NF-kB2
Tested Applications
ELISA, WB, IHC
Protein ID
117320527
Physical Properties
Liquid

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