SND1 Antibody

• Background:

  SND1 was originally characterized as a transcriptional coactivator for Epstein-Barr virus nuclear antigen 2. It is a STAT6 TAD interacting protein containing staphylococcal nuclease (SN) -like domain and tudor domain. p100 . The interaction is mediated by the TAD domain of STAT6 and the SN-like domain of SND1. SND1 associates with the large subunit of RNA polymerase II and is mediating interaction between STAT6 and RNA polymerase II. It was identified as a novel coactivator for STAT6 and suggest its functions as a bridging factor between STAT6 and the basal transcription machinery

• NCBI Gene ID:

  27044

• Swiss Prot:

  Q7KZF4

• Accession Number:

  NP_055205

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog, Zebrafish

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SND1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1207 - Raji Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SND1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  100 kDa

• Applications Notes:

  SND1 antibody can be used for detection of SND1 by ELISA at 1:62500. SND1 antibody can be used for detection of SND1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  SND1

• NCBI Official Name:

  Staphylococcal nuclease and tudor domain containing 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yang, J., et al., (2002) EMBO J. 21 (18), 4950-4958.

• Other Product Names:

  SND1, p100, TDRD11

• Tested Applications:

  ELISA, WB

• Protein ID:

  77404397

• Physical Properties:

  Liquid