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MAP3K7IP2 Antibody

CAT: 0223-27-585Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-585Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MAP3K7IP2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of NF.:B and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serving as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF.:B (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
NCBI Gene ID
23118
Swiss Prot
Q9NYJ8
Accession Number
NP_055908
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAP3K7IP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction, Immunology
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MAP3K7IP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
76 kDa
Applications Notes
MAP3K7IP2 antibody can be used for detection of MAP3K7IP2 by ELISA at 1:312500. MAP3K7IP2 antibody can be used for detection of MAP3K7IP2 by western blot at 2.0/mL.
Symbol
TAB2
NCBI Official Name
TGF-beta activated kinase 1/MAP3K7 binding protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Kanayama, A., et al., , (2004) Mol. Cell 15 (4), 535-548.
Other Product Names
MAP3K7IP2, CHTD2, MAP3K7IP2
Tested Applications
ELISA, WB, IHC
Protein ID
14149669
Physical Properties
Liquid