AEBP1 Antibody

• Background:

  The adipocyte enhancer binding protein 1 (AEBP1) is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. AEBP1 may play a role in differentiated vascular smooth muscle cells.

• NCBI Gene ID:

  165

• Swiss Prot:

  Q14113

• Accession Number:

  NP_001120

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AEBP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Signal Transduction

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store AEBP1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  131 kDa

• Applications Notes:

  AEBP1 antibody can be used for detection of AEBP1 by ELISA at 1:1562500. AEBP1 antibody can be used for detection of AEBP1 by western blot at 0.2-5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  AEBP1

• NCBI Official Name:

  AE binding protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Layne, M.D., et al., (1998) J.Biol.Chem.273 (25), 15654-15660.

• Other Product Names:

  AEBP1, ACLP

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  53692189

• Physical Properties:

  Liquid