TNRC4 Antibody

• Background:

  Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation.Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. While several transcript variants may exist for this gene, the full-length nature of only one has been biologically validated to date.

• NCBI Gene ID:

  11189

• Swiss Prot:

  Q5SZQ8

• Accession Number:

  NP_009116

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNRC4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Neuroscience

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TNRC4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  51 kDa

• Applications Notes:

  TNRC4 antibody can be used for detection of TNRC4 by ELISA at 1:1562500. TNRC4 antibody can be used for detection of TNRC4 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CELF3

• NCBI Official Name:

  CUGBP, Elav-like family member 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ladd, A.N., (2001) Mol. Cell. Biol. 21 (4), 1285-1296.

• Other Product Names:

  TNRC4, BRUNOL1, CAGH4, CELF3, ERDA4, MGC57297, TNRC4

• Tested Applications:

  ELISA, WB

• Protein ID:

  71164894

• Physical Properties:

  Liquid