CCNB1 Antibody

• Background :

  CCNB1 is a regulatory protein involved in mitosis. CCNB1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF) .The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF) . Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.

• NCBI Gene ID :

  891

• Swiss Prot :

  P14635

• Accession Number :

  NP_114172

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCNB1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Cancer

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CCNB1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  48 kDa

• Applications Notes :

  CCNB1 antibody can be used for detection of CCNB1 by ELISA at 1:312500. CCNB1 antibody can be used for detection of CCNB1 by western blot at 0.125 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  CCNB1

• NCBI Official Name :

  Cyclin B1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Zhao, M., (2006) Exp Oncol 28 (1), 44-48.

• Other Product Names :

  CCNB1, CCNB

• Tested Applications :

  ELISA, WB

• Protein ID :

  14327896

• Physical Properties :

  Liquid