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ID2 Antibody

CAT: 0223-27-257Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-257Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ID2 belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation.The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
3398
Swiss Prot
Q02363
Accession Number
NP_002157
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ID2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10426 - Fetal Thymus Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ID2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
15 kDa
Applications Notes
ID2 antibody can be used for detection of ID2 by ELISA at 1:1562500. ID2 antibody can be used for detection of ID2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ID2
NCBI Official Name
Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
NCBI Organism
Homo sapiens
Background Reference 01
Yang, J., (2008) Circ. Res. 102 (10), 1212-1221.
Other Product Names
ID2, GIG8, ID2A, ID2H, MGC26389, bHLHb26
Tested Applications
ELISA, WB
Protein ID
31982933
Physical Properties
Liquid

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