A2BP1 Antibody

• Background :

  Ataxin-2 binding protein 1 (A2BP1) has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2) . Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.

• NCBI Gene ID :

  54715

• Swiss Prot :

  Q9NWB1

• Accession Number :

  NP_001135805

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human A2BP1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Cat. No. 1219 - MCF7 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store A2BP1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  40 kDa

• Applications Notes :

  A2BP1 antibody can be used for detection of A2BP1 by ELISA at 1:62500. A2BP1 antibody can be used for detection of A2BP1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  RBFOX1

• NCBI Official Name :

  RNA binding protein, fox-1 homolog (C. elegans) 1

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  A2BP1, 2BP1, FOX1, A2BP1, FOX-1, HRNBP1

• Tested Applications :

  ELISA, WB

• Protein ID :

  215272410

• Physical Properties :

  Liquid