SCP2 Antibody

CAT: 0223-27-090Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-27-090Size:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
SCP2 protein is thought to be an intracellular lipid transfer protein. SCP2 is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis.This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined.
NCBI Gene ID
6342
Swiss Prot
Q6NXF4
Accession Number
NP_001007099
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SCP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1219 - MCF7 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SCP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
35 kDa
Applications Notes
SCP2 antibody can be used for detection of SCP2 by ELISA at 1:312500. SCP2 antibody can be used for detection of SCP2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SCP2
NCBI Official Name
Sterol carrier protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Stanley, W.A., (2007) Arch. Biochem. Biophys. 461 (1), 50-58.
Other Product Names
SCP2, DKFZp686C12188, DKFZp686D11188, NLTP, NSL-TP, SCPX, SCP-2, SCP-X, SCP-CHI
Tested Applications
ELISA, WB
Protein ID
55956775
Physical Properties
Liquid

Related Products

CatalogName
46-344SCP Antibody
46-344PSCP Peptide
64-160WAS Antibody
13-349WAS Antibody
60-596WAS Antibody
63-408DGKB Antibody
63-412AK5 Antibody
63-420HK3 Antibody
63-422HK2 Antibody
63-430YWHAZ Antibody

Alternative Products

CatalogName
MBS8594121-01SCP2 Antibody

Popular Products