ACO2 Antibody

• Background:

  ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

• NCBI Gene ID:

  50

• Swiss Prot:

  Q99798

• Accession Number:

  NP_001089

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, C. elegans

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ACO2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  721_B Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ACO2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  82 kDa

• Applications Notes:

  ACO2 antibody can be used for detection of ACO2 by ELISA at 1:312500. ACO2 antibody can be used for detection of ACO2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  ACO2

• NCBI Official Name:

  Aconitase 2, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yu, Z., (2006) Prostate 66 (10), 1061-1069.

• Other Product Names:

  ACO2, ACONM, MGC20605, MGC33908, ICRD

• Tested Applications:

  ELISA, WB

• Protein ID:

  4501867

• Physical Properties:

  Liquid