SPDYA Antibody

• Background:

  SPDYA regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.

• NCBI Gene ID:

  245711

• Swiss Prot:

  Q5MJ70

• Accession Number:

  NP_877433

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SPDYA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1201 - HeLa Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SPDYA antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  36 kDa

• Applications Notes:

  SPDYA antibody can be used for detection of SPDYA by ELISA at 1:62500. SPDYA antibody can be used for detection of SPDYA by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  SPDYA

• NCBI Official Name:

  Speedy/RINGO cell cycle regulator family member A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  McAndrew, C.W., (2007) Cell Cycle 6 (15), 1937-1945.

• Other Product Names:

  SPDYA, MGC110856, MGC57218, SPDY1, SPY1, RINGO3, RINGOA

• Tested Applications:

  ELISA, WB

• Protein ID:

  60498969

• Physical Properties:

  Liquid