POLL Antibody

• Background:

  POLL is a repair polymerase.It is involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.

• NCBI Gene ID:

  27343

• Swiss Prot:

  Q9UGP5

• Accession Number:

  NP_037406

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human POLL.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10123 - Fetal Brain Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store POLL antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  63 kDa

• Applications Notes:

  POLL antibody can be used for detection of POLL by ELISA at 1:12500. POLL antibody can be used for detection of POLL by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  POLL

• NCBI Official Name:

  Polymerase (DNA directed), lambda

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Picher, A.J. (2007) DNA Repair (Amst.) 6 (12), 1749-1756.

• Other Product Names:

  POLL, BETA-N, FLJ46002, POL-KAPPA, BETAN, POLKAPPA

• Tested Applications:

  ELISA, WB

• Protein ID:

  7019491

• Physical Properties:

  Liquid