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ALAS1 Antibody

CAT: 0223-26-853Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-26-853Size:100 µL
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Background
Delta-aminolevulinate synthase (ALAS; EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.
NCBI Gene ID
211
Swiss Prot
P13196
Accession Number
NP_000679
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ALAS1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10410 - Fetal Lung Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ALAS1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
70 kDa
Applications Notes
ALAS1 antibody can be used for detection of ALAS1 by ELISA at 1:312500. ALAS1 antibody can be used for detection of ALAS1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ALAS1
NCBI Official Name
Aminolevulinate, delta-, synthase 1
NCBI Organism
Homo sapiens
Background Reference 01
Jung, M., (2007) Urologe A 46 (9), 1083-1084.
Other Product Names
ALAS1, ALAS, ALAS3, ALASH, MIG4
Tested Applications
ELISA, WB
Protein ID
4502025
Physical Properties
Liquid

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