ERCC5 Antibody

• Background :

  Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, but the biological validity of all variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

• NCBI Gene ID :

  2073

• Swiss Prot :

  P28715

• Accession Number :

  NP_000114

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ERCC5.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Cat. No. XBL-10123 - Fetal Brain Tissue Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ERCC5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  133 kDa

• Applications Notes :

  ERCC5 antibody can be used for detection of ERCC5 by ELISA at 1:62500. ERCC5 antibody can be used for detection of ERCC5 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  ERCC5

• NCBI Official Name :

  Excision repair cross-complementing rodent repair deficiency, complementation group 5

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Sasaki, M., (2008) Neoplasia 10 (3), 255-265.

• Other Product Names :

  ERCC5, COFS3, ERCM2, UVDR, XPG, XPGC

• Tested Applications :

  ELISA, WB

• Protein ID :

  51988900

• Physical Properties :

  Liquid