GEFT Antibody

• Background :

  The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange.The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 [PubMed 11861769]) .

• NCBI Gene ID :

  115557

• Swiss Prot :

  Q86VW2

• Accession Number :

  NP_891992

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GEFT.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Cat. No. XBL-10123 - Fetal Brain Tissue Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GEFT antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  64 kDa

• Applications Notes :

  GEFT antibody can be used for detection of GEFT by ELISA at 1:312500. GEFT antibody can be used for detection of GEFT by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  ARHGEF25

• NCBI Official Name :

  Rho guanine nucleotide exchange factor (GEF) 25

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Lutz, S., (2007) Science 318 (5858), 1923-1927.

• Other Product Names :

  GEFT, p63RhoGEF, GEFT

• Tested Applications :

  ELISA, WB

• Protein ID :

  150417975

• Physical Properties :

  Liquid