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DCP1B Antibody

CAT: 0223-26-565Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-26-565Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DCP1B may play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. It may remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP.DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002 [PubMed 12417715]) .
NCBI Gene ID
196513
Swiss Prot
Q8IZD4
Accession Number
NP_689853
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DCP1B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
721_B Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DCP1B antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
68 kDa
Applications Notes
DCP1B antibody can be used for detection of DCP1B by ELISA at 1:62500. DCP1B antibody can be used for detection of DCP1B by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
DCP1B
NCBI Official Name
Decapping mRNA 1B
NCBI Organism
Homo sapiens
Background Reference 01
Beausoleil, S.A., (2006) Nat. Biotechnol. 24 (10), 1285-1292.
Other Product Names
DCP1B, DCP1, hDcp1b
Tested Applications
ELISA, WB
Protein ID
40548403
Physical Properties
Liquid

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