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PIGO Antibody

CAT: 0223-26-474Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-26-474Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PIGO is a protein that is involved in glycosylphosphatidylinositol (GPI) -anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. PIGO is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI.This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI) -anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least two alternatively spliced transcripts encoding distinct isoforms have been found for this gene.
NCBI Gene ID
84720
Swiss Prot
B1AML3
Accession Number
NP_690577
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PIGO.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1201 - HeLa Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PIGO antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
74 kDa
Applications Notes
PIGO antibody can be used for detection of PIGO by ELISA at 1:1562500. PIGO antibody can be used for detection of PIGO by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
PIGO
NCBI Official Name
Phosphatidylinositol glycan anchor biosynthesis, class O
NCBI Organism
Homo sapiens
Background Reference 01
Humphray, S.J., (2004) Nature 429 (6990), 369-374.
Other Product Names
PIGO, DKFZp434M222, FLJ00135, MGC20536, MGC3079, RP11-182N22.4, HPMRS2
Tested Applications
ELISA, WB
Protein ID
38045917
Physical Properties
Liquid

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