Products for Research Use Only
RegisterLogin

EDAR Antibody

CAT: 0223-26-441Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-26-441Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
EDAR is a member of the tumor necrosis factor receptor family. It is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in the gene encoding EDAR result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
10913
Swiss Prot
Q9UNE0
Accession Number
NP_071731
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EDAR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer, Signal Transduction, Apoptosis
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1309 - Human Placenta Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store EDAR antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
48 kDa
Applications Notes
EDAR antibody can be used for detection of EDAR by ELISA at 1:12500. EDAR antibody can be used for detection of EDAR by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
EDAR
NCBI Official Name
Ectodysplasin A receptor
NCBI Organism
Homo sapiens
Background Reference 01
RamaDevi, A.R., (2008) Br. J. Dermatol. 158 (1), 163-167.
Other Product Names
EDAR, DL, ED1R, ED3, ED5, EDA-A1R, EDA1R, EDA3, HRM1, ECTD10A, ECTD10B
Tested Applications
ELISA, WB
Protein ID
11641231
Physical Properties
Liquid

Related Products

CatalogName
90-297EDAR Recombinant Protein
8045-002mgEDA1 Antibody
8045-01EDA1 Antibody
8045-01mgEDA1 Antibody
25-972EDA Antibody
8045PEDA1 Peptide
92-636EDA2R Recombinant Protein
92-635EDA2R Recombinant Protein
90-288EDA-A1, Soluble Recombinant Protein
64-160WAS Antibody

Alternative Products

CatalogName
GTR18241473-01EDAR Antibody

Popular Products