LAPTM4B Antibody

• Background:

  LAPTM4B is a multi-pass membrane protein. It belongs to the LAPTM4/LAPTM5 transporter family. LAPTM4b has active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma.

• NCBI Gene ID:

  55353

• Swiss Prot:

  Q86VI4-3

• Accession Number:

  NP_060877

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LAPTM4B.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Cancer

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  293T Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store LAPTM4B antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  35 kDa

• Applications Notes:

  LAPTM4B antibody can be used for detection of LAPTM4B by ELISA at 1:62500. LAPTM4B antibody can be used for detection of LAPTM4B by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  LAPTM4B

• NCBI Official Name:

  Lysosomal protein transmembrane 4 beta

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Cheng, X.J., (2008) Ann. Oncol. 19 (3), 527-532.

• Other Product Names:

  LAPTM4B, LAPTM4beta, LC27

• Tested Applications:

  ELISA, WB

• Protein ID:

  30409982

• Physical Properties:

  Liquid