CLN6 Antibody

• Background:

  CLN6 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL) . Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely CLN6 involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

• NCBI Gene ID:

  54982

• Swiss Prot:

  Q9NWW5

• Accession Number:

  NP_060352

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLN6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10410 - Fetal Lung Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CLN6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  36 kDa

• Applications Notes:

  CLN6 antibody can be used for detection of CLN6 by ELISA at 1:1562500. CLN6 antibody can be used for detection of CLN6 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CLN6

• NCBI Official Name:

  Ceroid-lipofuscinosis, neuronal 6, late infantile, variant

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Heine, C., (2007) Mol. Membr. Biol. 24 (1), 74-87.

• Other Product Names:

  CLN6, FLJ20561, HsT18960, nclf, CLN4A

• Tested Applications:

  ELISA, WB

• Protein ID:

  8923532

• Physical Properties:

  Liquid