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ICMT Antibody

CAT: 0223-26-174Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-26-174Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ICMT is the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.
NCBI Gene ID
23463
Swiss Prot
O60725
Accession Number
NP_036537
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ICMT.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10407 - Fetal Heart Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ICMT antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
32 kDa
Applications Notes
ICMT antibody can be used for detection of ICMT by ELISA at 1:1562500. ICMT antibody can be used for detection of ICMT by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ICMT
NCBI Official Name
Isoprenylcysteine carboxyl methyltransferase
NCBI Organism
Homo sapiens
Background Reference 01
Lu, Q., (2007) Am. J. Respir. Cell Mol. Biol. 37 (1), 20-30.
Other Product Names
ICMT, HSTE14, MGC39955, MST098, MSTP098, PCCMT, PCMT, PPMT
Tested Applications
ELISA, WB
Protein ID
6912430
Physical Properties
Liquid

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