ICMT Antibody

• Background:

  ICMT is the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.

• NCBI Gene ID:

  23463

• Swiss Prot:

  O60725

• Accession Number:

  NP_036537

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ICMT.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Signal Transduction

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10407 - Fetal Heart Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ICMT antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  32 kDa

• Applications Notes:

  ICMT antibody can be used for detection of ICMT by ELISA at 1:1562500. ICMT antibody can be used for detection of ICMT by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  ICMT

• NCBI Official Name:

  Isoprenylcysteine carboxyl methyltransferase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lu, Q., (2007) Am. J. Respir. Cell Mol. Biol. 37 (1), 20-30.

• Other Product Names:

  ICMT, HSTE14, MGC39955, MST098, MSTP098, PCCMT, PCMT, PPMT

• Tested Applications:

  ELISA, WB

• Protein ID:

  6912430

• Physical Properties:

  Liquid