IFNAR2 Antibody

• Background:

  The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.

• NCBI Gene ID:

  3455

• Swiss Prot:

  P48551

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 27-243 of human IFNAR2 (NP_997467.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction, Inflammasomes

• Purification:

  Affinity purification

• Positive Control:

  MCF7

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 58kDa

• Fragment:

  IgG

• Symbol:

  IFNAR2

• Positive Control 2:

  Raji

• Positive Control 3:

  HepG2

• Positive Control 4:

  THP-1

• Positive Control 5:

  SW480

• Positive Control 6:

  A-549

• NCBI Official Name:

  Interferon (alpha, beta and omega) receptor 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  IFNAR2, interferon (alpha, beta and omega) receptor 2, IFN-R, IFN-alpha-REC, IFNABR, IFNARB

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid