ABCC9 Antibody

ABCC9 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. No disease has been associated with this gene thus far. Alternative splicing of this gene results in several products, two of which result from differential usage of two terminal exons and one of which results from exon deletion. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. No disease has been associated with this gene thus far. Alternative splicing of this gene results in several products, two of which result from differential usage of two terminal exons and one of which results from exon deletion.

10060

O60706

NP_005682

Human, Mouse, Rat

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ABCC9.

Unconjugated

Primary Antibodies

Membrane, Signal Transduction

Antibody is purified by peptide affinity chromatography method.

721_B Cell Lysate

Batch dependent

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

None

Blue Ice

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ABCC9 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

174 kDa

ABCC9 antibody can be used for detection of ABCC9 by ELISA at 1:1562500. ABCC9 antibody can be used for detection of ABCC9 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

ABCC9

ATP-binding cassette, sub-family C (CFTR/MRP), member 9

Homo sapiens

Burke, M.A., (2008) Circ. Res. 102 (2), 164-176.

ABCC9, ABC37, CMD1O, FLJ36852, SUR2, CANTU, ATFB12

ELISA, WB

110832835