Products for Research Use Only
RegisterLogin

RNF19A Antibody

CAT: 0223-25-832Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-25-832Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
RNF19A contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB.The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.
NCBI Gene ID
25897
Swiss Prot
Q9NV58
Accession Number
NP_056250
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF19A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RNF19A antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
91 kDa
Applications Notes
RNF19A antibody can be used for detection of RNF19A by ELISA at 1:1562500. RNF19A antibody can be used for detection of RNF19A by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RNF19A
NCBI Official Name
Ring finger protein 19A, RBR E3 ubiquitin protein ligase
NCBI Organism
Homo sapiens
Background Reference 01
Ishigaki, S., (2007) Neurobiol. Dis. 25 (2), 331-341.
Other Product Names
RNF19A, DKFZp566B1346, DORFIN, RNF19
Tested Applications
ELISA, WB
Protein ID
35493782
Physical Properties
Liquid

Related Products

CatalogName
55-689RNF19B Antibody
46-303RNF125 Antibody
60-505RNF135 Antibody
29-850RNF121 Antibody
8285-002mgRNF121 Antibody
59-964RNF111 Antibody
27-746RNF130 Antibody
25-819RNF139 Antibody
13-567RNF138 Antibody
23-328RNF125 Antibody

Alternative Products

CatalogName
70R-6263RNF19A antibody

Popular Products