TJP2 Antibody

• Background:

  Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.

• NCBI Gene ID:

  9414

• Swiss Prot:

  A2A3H9

• Accession Number:

  NP_963923

• Host:

  Rabbit

• Reactivity:

  Human, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TJP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TJP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  118 kDa

• Applications Notes:

  TJP2 antibody can be used for detection of TJP2 by ELISA at 1:62500. TJP2 antibody can be used for detection of TJP2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  TJP2

• NCBI Official Name:

  Tight junction protein 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bel (2008) Hum. Genet. 123 (3), 267-272.

• Other Product Names:

  TJP2, MGC26306, X104, ZO-2, ZO2, DFNA51, DUP9q21.11, C9DUPq21.11

• Tested Applications:

  ELISA, WB

• Protein ID:

  42518065

• Physical Properties:

  Liquid