ELMO3 Antibody

• Background:

  ELMO3 is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes.The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes.

• NCBI Gene ID:

  79767

• Swiss Prot:

  Q96BJ8

• Accession Number:

  NP_078988

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ELMO3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Apoptosis

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  721_B Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ELMO3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  87 kDa

• Applications Notes:

  ELMO3 antibody can be used for detection of ELMO3 by ELISA at 1:312500. ELMO3 antibody can be used for detection of ELMO3 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  ELMO3

• NCBI Official Name:

  Engulfment and cell motility 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Gumienny, T.L., (2001) Cell 107 (1), 27-41.

• Other Product Names:

  ELMO3, CED-12, CED12, ELMO-3, FLJ13824

• Tested Applications:

  ELISA, WB

• Protein ID:

  87298935

• Physical Properties:

  Liquid