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SNUPN Antibody

CAT: 0223-25-631Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-25-631Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. SNUPN interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor.The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
NCBI Gene ID
10073
Swiss Prot
O95149
Accession Number
NP_005692
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SNUPN.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10407 - Fetal Heart Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SNUPN antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
41 kDa
Applications Notes
SNUPN antibody can be used for detection of SNUPN by ELISA at 1:62500. SNUPN antibody can be used for detection of SNUPN by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SNUPN
NCBI Official Name
Snurportin 1
NCBI Organism
Homo sapiens
Background Reference 01
Ospina, J.K., (2005) Mol. Biol. Cell 16 (10), 4660-4671.
Other Product Names
SNUPN, KPNBL, RNUT1, Snurportin1
Tested Applications
ELISA, WB
Protein ID
5031833
Physical Properties
Liquid

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