CSTF3 Antibody

• Background:

  CSTF3 is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF) . This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF) . This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms.

• NCBI Gene ID:

  1479

• Swiss Prot:

  Q12996

• Accession Number:

  NP_001317

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CSTF3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  721_B Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CSTF3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  83 kDa

• Applications Notes:

  CSTF3 antibody can be used for detection of CSTF3 by ELISA at 1:312500. CSTF3 antibody can be used for detection of CSTF3 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CSTF3

• NCBI Official Name:

  Cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007) .

• Other Product Names:

  CSTF3, CSTF-77, MGC117398, MGC43001, MGC75122

• Tested Applications:

  ELISA, WB

• Protein ID:

  4557495

• Physical Properties:

  Liquid