MSL3L1 Antibody

• Background:

  MSL3L1 is a nuclear protein, which is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. This gene encodes a nuclear protein and has similarity to drosophila male-specific lethal-3 gene. The drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus this encoded protein is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. There are four alternatively spliced transcript variants of this gene encoding different isoforms.

• NCBI Gene ID:

  10943

• Swiss Prot:

  Q8N5Y2

• Accession Number:

  NP_523353

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MSL3L1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  293T Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MSL3L1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  60 kDa

• Applications Notes:

  MSL3L1 antibody can be used for detection of MSL3L1 by ELISA at 1:62500. MSL3L1 antibody can be used for detection of MSL3L1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  MSL3

• NCBI Official Name:

  Male-specific lethal 3 homolog (Drosophila)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Smith, E.R., (2005) Mol. Cell. Biol. 25 (21), 9175-9188.

• Other Product Names:

  MSL3L1, DKFZP586J1822, MSL3L1

• Tested Applications:

  ELISA, WB

• Protein ID:

  212275945

• Physical Properties:

  Liquid