PEO1 Antibody

• Background:

  Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars.Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars (Spelbrink et al., 2001 [PubMed 11431692]) .

• NCBI Gene ID:

  56652

• Swiss Prot:

  Q96RR1

• Accession Number:

  NP_068602

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PEO1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Homeostasis

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PEO1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  77 kDa

• Applications Notes:

  PEO1 antibody can be used for detection of PEO1 by ELISA at 1:312500. PEO1 antibody can be used for detection of PEO1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  C10orf2

• NCBI Official Name:

  Chromosome 10 open reading frame 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Farge, G., (2008) Nucleic Acids Res. 36 (2), 393-403.

• Other Product Names:

  PEO1, C10orf2, FLJ21832, PEO, PEOA3, SANDO, TWINL, PEO1, SCA8, ATXN8, IOSCA, MTDPS7

• Tested Applications:

  ELISA, WB

• Protein ID:

  39725942

• Physical Properties:

  Liquid