LASS5 Antibody

• Background:

  LASS5 may be either a bona fide (dihydro) ceramide synthase or a modulator of its activity. When it is overexpressed in cells it is involved in the production of sphingolipids containing mainly only one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner.

• NCBI Gene ID:

  91012

• Swiss Prot:

  Q8N5B7

• Accession Number:

  NP_671723

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LASS5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Membrane

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10408 - Fetal Kidney Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store LASS5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  46 kDa

• Applications Notes:

  LASS5 antibody can be used for detection of LASS5 by ELISA at 1:12500. LASS5 antibody can be used for detection of LASS5 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CERS5

• NCBI Official Name:

  Ceramide synthase 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kitatani, K., (2006) J. Biol. Chem. 281 (48), 36793-36802.

• Other Product Names:

  LASS5, CerS5, FLJ25304, MGC45411, Trh4, LASS5

• Tested Applications:

  ELISA, WB

• Protein ID:

  22218345

• Physical Properties:

  Liquid