LASS1 Antibody

• NCBI Gene ID:

  10715

• Swiss Prot:

  P27544

• Accession Number:

  NP_067090.1, NP_937850.1

• Host:

  Goat

• Reactivity:

  Human

• Immunogen:

  The immunogen for this antibody is: C-KDLREYDTAEAQ

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

• Positive Control:

  Cat. No. 1366 - Human Frontal Lobe Tissue Lysate

• Concentration:

  500 ug/mL

• Homology:

  Expected Species Reactivity based on sequence homology: Mouse, Pig, Cow

• Buffer:

  Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and store at -20˚ C. Minimize freezing and thawing.

• Specificity:

  This antibody is expected to recognize both reported isoforms (NP_067090.1and NP_937850.1) .

• Applications Notes:

  Peptide ELISA: Western Blot:

• Symbol:

  LASS1

• NCBI Official Name:

  Ceramide synthase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Venkataraman K, Riebeling C, Bodennec J, Riezman H, Allegood JC, Sullards MC, Merrill AH Jr, Futerman AH. Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18- (dihydro) ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells. J Biol Chem. 2002 Sep 20;277 (38) :35642-9. Epub 2002 Jun 24.

• Other Product Names:

  LAG1, CerS1, LASS1, LAG1 homolog, ceramide synthase 1, MGC90349, UOG1, LAG1 longevity assurance homolog 1, longevity assurance (LAG1, S. cerevisiae) homolog 1, longevity assurance gene 1, upstream of GDF1

• Tested Applications:

  ELISA, WB

• Protein ID:

  11641421

• Physical Properties:

  Liquid