SLC18A1 Antibody

CAT: 0223-25-274Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-25-274Size:100 µL
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Background
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazineThe vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]) . See also SLC18A2 (MIM 193001) .
NCBI Gene ID
6570
Swiss Prot
P54219
Accession Number
NP_003044
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC18A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SLC18A1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
56 kDa
Applications Notes
SLC18A1 antibody can be used for detection of SLC18A1 by ELISA at 1:62500. SLC18A1 antibody can be used for detection of SLC18A1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SLC18A1
NCBI Official Name
Solute carrier family 18 (vesicular monoamine transporter), member 1
NCBI Organism
Homo sapiens
Background Reference 01
Lohoff, F.W., (er) Neuropsychobiology 57 (1-2), 55-60 (2008) In press.
Other Product Names
SLC18A1, CGAT, VAT1, VMAT1
Tested Applications
ELISA, WB
Protein ID
4506987
Physical Properties
Liquid

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