SLC11A1 Antibody

• Background:

  SLC11A1 is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and is a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in its gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease.

• NCBI Gene ID:

  6556

• Swiss Prot:

  P49279

• Accession Number:

  NP_000569

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC11A1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Cancer

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SLC11A1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  61 kDa

• Applications Notes:

  SLC11A1 antibody can be used for detection of SLC11A1 by ELISA at 1:1562500. SLC11A1 antibody can be used for detection of SLC11A1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  SLC11A1

• NCBI Official Name:

  Solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Awomoyi, A., (2006) Int. J. Immunogenet. 33 (1), 11-15.

• Other Product Names:

  SLC11A1, LSH, NRAMP, NRAMP1

• Tested Applications:

  ELISA, WB

• Protein ID:

  109255241

• Physical Properties:

  Liquid