CCRL2 Antibody

CCRL2 is a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. CCRL2 gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.

9034

O00421

NP_003956

Human

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCRL2.

Unconjugated

Primary Antibodies

Membrane, Signal Transduction, Immunology

Antibody is purified by peptide affinity chromatography method.

721_B Cell Lysate

Batch dependent

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

None

Blue Ice

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CCRL2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

39 kDa

CCRL2 antibody can be used for detection of CCRL2 by ELISA at 1:1562500. CCRL2 antibody can be used for detection of CCRL2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

CCRL2

Chemokine (C-C motif) receptor-like 2

Homo sapiens

Galligan, C.L., (2004) Arthritis Rheum. 50 (6), 1806-1814.

CCRL2, CKRX, CRAM-A, CRAM-B, HCR, MGC116710, CRAM, ACKR5, CCRL2

ELISA, WB

68215224