TFCP2 Antibody

• Background:

  TFCP2 binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. It also functions as part of the SSP (stage selector protein) complex. TFCP2 facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. It interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.

• NCBI Gene ID:

  7024

• Swiss Prot:

  Q12800

• Accession Number:

  NP_005644

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TFCP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  293T Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TFCP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  57 kDa

• Applications Notes:

  TFCP2 antibody can be used for detection of TFCP2 by ELISA at 1:312500. TFCP2 antibody can be used for detection of TFCP2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  TFCP2

• NCBI Official Name:

  Transcription factor CP2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Randall, C.N., (er) Neurochem. Res. (2008) In press.

• Other Product Names:

  TFCP2, CP2, LBP-1C, LSF, SEF, TFCP2C, LBP1C, LSF1D

• Tested Applications:

  ELISA, WB

• Protein ID:

  21361278

• Physical Properties:

  Liquid