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GLDC Antibody

CAT: 0223-23-982Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-23-982Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase) . The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH) .
NCBI Gene ID
2731
Swiss Prot
P23378
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 36-290 of human GLDC (NP_000161.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 113kDa
Fragment
IgG
Symbol
GLDC
Positive Control 2
DU145
NCBI Official Name
Glycine dehydrogenase (decarboxylating), mitochondrial
NCBI Organism
Homo sapiens
Other Product Names
Glycine dehydrogenase (decarboxylating), mitochondrial, Glycine cleavage system P protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring), GLDC, GCSP
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

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