ERC1 Antibody

• Background:

  The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t (10;12) (q11; p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  23085

• Swiss Prot:

  Q8IUD2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 700-850 of human ERC1 (NP_829884.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Immunology, Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 130 120kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  ERC1

• Positive Control 2:

  Jurkat

• Positive Control 3:

  NIH/3T3

• Positive Control 4:

  Rat brain

• NCBI Official Name:

  ELKS/RAB6-interacting/CAST family member 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ERC1, ELKS/RAB6-interacting/CAST family member 1, Cast2, ELKS, KIAA1081, MGC12974, RAB6IP2, RAB6 interacting protein 2, RAB6-interacting protein 2, Rab6-interacting protein 2

• Tested Applications:

  WB

• Physical Properties:

  Liquid