THOP1 Antibody

• Background:

  The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides.

• NCBI Gene ID:

  7064

• Swiss Prot:

  P52888

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human THOP1 (NP_003240.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  Mouse skeletal muscle

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 79kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  THOP1

• Positive Control 2:

  Mouse heart

• Positive Control 3:

  Mouse lung

• Positive Control 4:

  Rat liver

• Positive Control 5:

  Rat kidney

• NCBI Official Name:

  Thimet oligopeptidase 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  EP24.15, MEPD_HUMAN, MP78, TOP, thimet oligopeptidase, endopeptidase 24.15

• Tested Applications:

  WB

• Physical Properties:

  Liquid