PPP6R2 Antibody

• Background:

  The protein encoded by this gene is a regulatory protein for the protein phosphatase-6 catalytic subunit. Together, these proteins act as a significant T-loop phosphatase for Aurora A, an essential mitotic kinase. Loss of function of either the regulatory or catalytic subunit of protein phosphatase-6 interferes with spindle formation and chromosome alignment.

• NCBI Gene ID:

  9701

• Swiss Prot:

  O75170

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 640-959 of human PPP6R2 (NP_001229827.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 105kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  PPP6R2

• Positive Control 2:

  293T

• Positive Control 3:

  Jurkat

• NCBI Official Name:

  Protein phosphatase 6 regulatory subunit 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  KIAA0685, PP6R2, SAP19SAPS2, serine/threonine-protein phosphatase 6 regulatory subunit 2, SAPS domain family, member 2

• Tested Applications:

  WB

• Physical Properties:

  Liquid