PPP1R8 Antibody

This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

5511

Q6IonChannelT4

NP_002704

Human, Mouse, Rat, Dog

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PPP1R8.

Unconjugated

Primary Antibodies

Other

Antibody is purified by protein A chromatography method.

Cat. No. XBL-10426 - Fetal Thymus Tissue Lysate

Batch dependent

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

None

Blue Ice

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PPP1R8 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

14 kDa, 38 kDa, 23 kDa

PPP1R8 antibody can be used for detection of PPP1R8 by ELISA at 1:312500. PPP1R8 antibody can be used for detection of PPP1R8 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

PPP1R8

Protein phosphatase 1, regulatory subunit 8

Homo sapiens

Lesage, B., (2004) J. Biol. Chem. 279 (53), 55978-55984.

PPP1R8, ARD1, ARD-1, NIPP1, NIPP-1, PRO2047

ELISA, WB, IHC

4506015