LLGL2 Antibody

• Background:

  The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC) . In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

• NCBI Gene ID:

  217325

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 620-819 of mouse LLGL2 (NP_663413.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  MCF7

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 113kDa

• Fragment:

  IgG

• Symbol:

  LLGL2

• Positive Control 2:

  Mouse liver

• Positive Control 3:

  Rat liver

• NCBI Official Name:

  LLGL2 scribble cell polarity complex component

• NCBI Organism:

  Mus musculus

• Other Product Names:

  9130006H11Rik, Llglh2, lethal (2) giant larvae protein homolog 2, lethal giant larvae-like protein 2

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid