LLGL2 Antibody

• Background :

  The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC) . In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

• NCBI Gene ID :

  217325

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 620-819 of mouse LLGL2 (NP_663413.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle

• Purification :

  Affinity purification

• Positive Control :

  MCF7

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 113kDa

• Fragment :

  IgG

• Symbol :

  LLGL2

• Positive Control 2 :

  Mouse liver

• Positive Control 3 :

  Rat liver

• NCBI Official Name :

  LLGL2 scribble cell polarity complex component

• NCBI Organism :

  Mus musculus

• Other Product Names :

  9130006H11Rik, Llglh2, lethal (2) giant larvae protein homolog 2, lethal giant larvae-like protein 2

• Tested Applications :

  WB, IHC, IF

• Physical Properties :

  Liquid