Products for Research Use Only
RegisterLogin

ALOXE3 Antibody

CAT: 0223-23-475Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-23-475Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE) . This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE) . Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
59344
Swiss Prot
Q9BYJ1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ALOXE3 (NP_067641.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
22Rv1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 81kDa
Fragment
IgG
Symbol
ALOXE3
Positive Control 2
MCF7
Positive Control 3
Mouse skeletal muscle
Positive Control 4
Mouse testis
Positive Control 5
Rat intestine
NCBI Official Name
Hydroperoxide isomerase ALOXE3
NCBI Organism
Homo sapiens
Other Product Names
Hydroperoxide isomerase ALOXE3, Epidermis-type lipoxygenase 3, Epidermal LOX-3, e-LOX-3, eLOX-3, Hydroperoxy icosatetraenoate dehydratase, ALOXE3
Tested Applications
WB, IF
Physical Properties
Liquid

Related Products

CatalogName
63-684ALOX12 Antibody
63-276ALOX15 Antibody
22-513ALOX15 Antibody
15-675ALOX12 Antibody
46-769ALOX15 Antibody
18-543ALOX5 Antibody
46-769PALOX15 Peptide
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody

Alternative Products

CatalogName
abx005761-01Hydroperoxide Isomerase ALOXE3 (ALOXE3) Antibody
MBS854027-01ALOXE3 Antibody

Popular Products