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CKMT2 Antibody

CAT: 0223-23-392Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-23-392Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
1160
Swiss Prot
P17540
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 40-230 of human CKMT2 (NP_001816.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 40kDa
Fragment
IgG
Symbol
CKMT2
Positive Control 2
Mouse skeletal muscle
Positive Control 3
Mouse heart
Positive Control 4
Mouse diaphragm
Positive Control 5
Rat skeletal muscle
NCBI Official Name
Creatine kinase, mitochondrial 2 (sarcomeric)
NCBI Organism
Homo sapiens
Other Product Names
CKMT2, SMTCK
Tested Applications
WB, IHC
Physical Properties
Liquid

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