LEPREL2 Antibody

• Background:

  The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor.

• NCBI Gene ID:

  10536

• Swiss Prot:

  Q8IVL6

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 487-736 of human LEPREL2 (NP_055077.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  22Rv1

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 82kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  LEPREL2

• Positive Control 2:

  NIH/3T3

• Positive Control 3:

  Mouse skeletal muscle

• NCBI Official Name:

  Prolyl 3-hydroxylase 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  GRCB, HSU47926, LEPREL2, prolyl 3-hydroxylase 3, gene rich cluster, B, leprecan-like 2, procollagen-proline 3-dioxygenase, protein B

• Tested Applications:

  WB

• Physical Properties:

  Liquid