EYA3 Antibody

• Background:

  This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.

• NCBI Gene ID:

  2140

• Swiss Prot:

  Q99504

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human EYA3 (NP_001981.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 63kDa

• Fragment:

  IgG

• Symbol:

  EYA3

• Positive Control 2:

  293T

• Positive Control 3:

  HT-29

• Positive Control 4:

  Mouse liver

• Positive Control 5:

  Mouse eye

• Positive Control 6:

  Rat eye

• NCBI Official Name:

  Eyes absent homolog 3 (Drosophila)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  EYA3

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid